Universal Screening for G6PD Deficiency Detects More Cases Than Selective Testing
نویسندگان
چکیده
منابع مشابه
Screening for G6pd Deficiency in Blood Donors
Original Article AIMS AND OBJECTIVES:1. To screen blood donors [n=100] for G6PD deficiency, particularly in males. 2. To determine the frequency of G6PD deficiency in the population tested. MATERIALS AND METHODS: 50 samples of donors' blood from at KIMS Blood Bank. Method of collection of data: The Methaemoglobin reduction test: Principle: Sodium Nitrate oxidises MethHb to Hb and the subsequent...
متن کاملSemiquantitative screening test for G6PD deficiency detects severe deficiency but misses a substantial proportion of partially-deficient females.
Neonatal screening for G6PD deficiency has long been established in many countries. The aim of the study was to determine whether the routine semiquantitative fluorescent spot test could detect all cases of G6PD deficiency, including those cases with partial deficiency (residual red cell G6PD activity between 20-60% of normal). We compared the results of G6PD screening by the semiquantitative f...
متن کاملNeonatal Screening for G6PD Deficiency in Mazandaran Province, Iran 2007-2010
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common disease of the hexose monophosphate pathway existing in more than 400 million people worldwide. The aim of this study was to identify neonates with G6PD deficiency following national program for screening and education of affected newborns’ parents started since June 2007 in Mazandaran, a northern Province of Ira...
متن کاملG6PD deficiency.
T HIRTY-FIVE YEARS ago Dr William Dameshek, the first editor of the emerging journal Blood, invited me to write a review on “The Hemolytic Effect of Primaquine.”’ At the time, primaquine sensitivity, which had just recently been shown to be caused by a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD); represented a unique example of an inherited deficiency of an enzyme that cau...
متن کاملPrevalence of G6PD deficiency in neonates referred to Semnan University of Medical Science´s screening Lab
Abstract Background and objectives: Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway. G6PD deficiency (an X-linked recessive hereditary disease) is an inherited condition affecting approximately 3% of the people globally. This deficiency can cause hemolytic anemia and jaundice in neonates. The goal of this study is to detect the prevalence of G6PD deficienc...
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ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v128.22.1261.1261